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– How can the risk of developing OA, as well as those who may be in the early stages of the disease, before they develop symptoms? – How effective are different strategies for preventing OA, including weight control, exercise and gait modification? – What are the underlying disease mechanisms? the role the role of biomechanics, joint injury, inflammation and aging in the pathogenesis and progression? – What are the advantages and challenges associated with the current medical and surgical treatments for OA are connected? What is the promise of more efficient medical, surgical and new tissue engineering strategies for the prevention and treatment?Compulsory tests for the proper diagnosis of IC are history, physical examination and urine tests. Featured assays include urine culture and cytology, symptoms and quality of life tools, frequency – volumetric charts for, residual urine measurement of and psa Cystoscopy with and without hydrodistension. Ultrasound imaging, urodynamics, CT imaging, intravesical potassium and bladder biopsy testing are all optional.