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Anti-VEGF therapy benefits in wet AMD not sustained By Lucy Piper, Senior medwireNews Reporter Real-world connection with anti-vascular endothelial growth aspect therapy for individuals with wet age-related macular degeneration suggests that initial improvements in visual acuity are not maintained as time passes. The trial involved ranibizumab, intravitreal injections of which have led to significant improvements in visible acuity which have been managed with regular monthly treatment in scientific trials. Visible acuity improved until about time 120, after which visual gains weren’t maintained. The average change in visible acuity from baseline was +2.4 letters at 12 months and +0.6 letters at 24 months.

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