Mouse Model Advances understanding Synovial sarcomaA mouse model of synovial sarcoma has scientists enabled tremendous progress in understanding the origin and pathogenesis make this highly aggressive soft tissue malignancy. The research published in the April issue of the journal Cancer Cell, published by Cell Press, provides new information on the time and the environment for the initiation and progression of synovial sarcoma required. The mouse model is likely to invaluable resource for invaluable resource for the development of novel treatment strategies for this often deadly cancer stable perfomance .

Synovial sarcoma with expression of a chimeric fusion protein called SYT – SSX connected. Mario R. Capecchi, of the Howard Hughes Medical Institute and the Department of Human Genetics at the University of Utah School of Medicine and colleagues have developed a mouse model that expresses human SYT – SSX in selected target cells. With this approach the researchers discovered, even though it is named for its common proximity to limb joints, Earlierskeletal muscle progenitor cells seems to arise as myoblasts. Notably, the expression of SYT-SSX in myoblasts was sufficient to induce synovial sarcoma with an amazing 100 percent penetrance.

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The Company has an pilot study on clinical study on the safety of its Renal Guard treatment and de Renal Guard System in December 2007. To this end the company received CE Ask certification for Renal Guard System. The kidneys SafeGuard therapeutic was designed by reduced the toxic effects that contrast to has on the kidneys. This therapy is based on theory of that the creation of and maintain high urinary output is beneficial for patients, imaging processes when contrast media be based using. The real-time measurement and matched rehydration style the system Renal Guard will ensure that a high level of urination upright consent , during and after such processes. This should allow body of about contrast, contrast, reducing the toxic effects. The Renal Guard System, and its matched fluid replacement capability is to the risk the risk out of over-or under – hydratation. – For more information about the company can be found at.

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